Nonribosomal antibacterial peptides that target multidrug-resistant bacteria
نویسندگان
چکیده
منابع مشابه
Antibacterial peptides from thermophilic bacteria
It is becoming interestingly apparent that innovations of the classical antibiotics are not effective, that induces need for novel drugs. Peptide antibiotics exhibit a group of secondary metabolites with hydrophobic and cyclic structures containing d-amino acidc like compounds with more resistant to proteolytic degradation. Bacterial peptides can possess bactericidal, fungicidal, metal chelatin...
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Multidrug-resistant pathogens have become a major public health concern. There is a great need for the development of novel antibiotics with alternative mechanisms of action for the treatment of life-threatening bacterial infections. Antimicrobial peptides, a major class of antibacterial agents, share amphiphilicity and cationic structural properties with cell-penetrating peptides (CPPs). Herei...
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ژورنال
عنوان ژورنال: Natural Product Reports
سال: 2019
ISSN: 0265-0568,1460-4752
DOI: 10.1039/c8np00031j